Background to another flawed study - intactness and cervical cancer

Background to the rebuttal to another biased study

Funding, sources, references, authors

Funded by grants from the European Community (CI 1-0371-F(CD)); the Fondo de Investigaciones Sanitarias (FIS), Spain (86/753, 87/1513, 88/2049, 90/0901, 95/0955, 01/1237, 01/1236, and BAE 01/5013); the International Agency for Research on Cancer, Lyons, France (FI/92/3-2 PAR); Preventiefonds, the Netherlands (28-1502€1); Programa Interministerial de Investigación y Desarrollo, Spain (SAF 96/0323); the Conselho Nacional de Desenvolvimiento Cientifico e Tecnologico, Brazil (JEN-204453/88€7); the Department of Reproductive Health and Research of the World Health Organization (98€101); and a Union International contre le Cancer Yamagiwa-Yoshida Memorial International Cancer Study Grant.

We are indebted to the women and men who participated in the study; to the gynecologists, pathologists, oncologists, and supervisors involved in the fieldwork that made the original studies possible; and to A. Arslan and M. Diaz for their technical assistance in data management.

Source Information

From the Servei d'Epidemiologia i Registre del Càncer, Institut Català d'Oncologia, Hospitalet de Llobregat, Barcelona, Spain (X.C., F.X.B., S.S.); the International Agency for Research on Cancer, Lyons, France (N.M., J.S.S., R.H., S.F.); Free University Hospital, Amsterdam (C.J.L.M.M.); Johns Hopkins University, Baltimore (K.V.S.); Universidade de São Paulo, São Paulo, Brazil (J.E.-N.); Philippine General Hospital, University of the Philippines, Manila, the Philippines (C.A.N.); the Faculty of Medicine, Prince of Songkla University, Hat-Yai, Thailand (S.C.); and Proyecto Epidemiológico Guanacaste, San José, Costa Rica (R.H.).

Victor Moreno, M.D., Servei d'Epidemiologia i Registre del Càncer, Institut Català d'Oncologia, Hospitalet de Llobregat, Barcelona, Spain, was also an author.

Address reprint requests to Dr. Castellsagué at the Servei d'Epidemiologia i Registre del Càncer, Institut Català d'Oncologia, Gran Via s/n, Km 2.7, 08907 Hospitalet de Llobregat, Barcelona, Spain, or at xcastellsague@ico.scs.es.

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Appendix

The members of the International Agency for Research on Cancer (IARC) Multicenter Cervical Cancer Study Group are as follows: N. Muñoz, S. Franceschi, J.S. Smith, M. Plummer, IARC, Lyons, France; F.X. Bosch, S. de Sanjosé, X. Castellsagué, V. Moreno, Institut Català d'Oncologia, Barcelona, Spain; L.C. González, Servicio Territorial de Sanidad y Bienestar Social, Salamanca, Spain; M. Gili, Universidad de Sevilla, Seville, Spain; I. Izarzugaza, Euskadi Cancer Registry, Vitoria-Gasteiz, Spain; P. Viladiu, Registre de Càncer de Catalunya, Barcelona, Spain; C. Navarro, Consejería de Sanidad, Murcia, Spain; A. Vergara, Servicio Provincial de Sanidad, Zaragoza, Spain; N. Ascunce, Programa de Cáncer de Mama, Pamplona, Spain; M. Santamaria, Hospital de Navarra, Pamplona, Spain; C.J.L.M. Meijer, J.M.M. Walboomers, P.J. Snijders, A.J. van den Brule, Free University Hospital, Amsterdam; K.V. Shah, Johns Hopkins University, Baltimore; R. Herrero, Proyecto Epidemiológico Guanacaste, San José, Costa Rica; L. Tafur, N. Aristizabal, Universidad de Valle, Cali, Colombia; P. Alonso de Ruiz, General Hospital of Mexico, Mexico City, Mexico; S. Chichareon, Prince of Songkla University, Hat-Yai, Thailand; C. Ngelangel, University of the Philippines, Manila, the Philippines; and J. Eluf-Neto, Universidade de São Paulo, São Paulo, Brazil.

This article has been cited by other articles:

Adami, H.-O., Trichopoulos, D. (2002). Cervical Cancer and the Elusive Male Factor. N Engl J Med 346: 1160-1161 [Full Text]

References to the editorial by Adami and Trichopolous

1. Moses S, Bailey RC, Ronald AR. Male circumcision: assessment of health benefits and risks. Sex Transm Infect 1998;74:368-373.[Abstract]

2. American Academy of Pediatrics, Task Force on Circumcision. Circumcision policy statement. Pediatrics 1999;103:686-693.[Abstract/Full Text]

3. Castellsagué X, Bosch FX, Muñoz N, et al. Male circumcision, penile human papillomavirus infection, and cervical cancer in female partners. N Engl J Med 2002;346:1105-1112.

4. Circumcision and cervical cancer. Lancet 1966;1:137-137.[Medline]

5. Brinton LA, Reeves WC, Brenes MM, et al. The male factor in the etiology of cervical cancer among sexually monogamous women. Int J Cancer 1989;44:199-203.[Medline]

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7. Tsen HF, Morgenstern H, Mack T, Peters RK. Risk factors for penile cancer: results of a population-based case-control study in Los Angeles County (United States). Cancer Causes Control 2001;12:267-277.[Medline]

8. Lavreys L, Rakwar JP, Thompson ML, et al. Effect of circumcision on incidence of human immunodeficiency virus type 1 and other sexually transmitted diseases: a prospective cohort study of trucking company employees in Kenya. J Infect Dis 1999;180:330-336.[Medline]

9. Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001;94:153-156.[Medline]

10. Lowy DR, Schiller JT. Papillomaviruses and cervical cancer: pathogenesis and vaccine development. In: First National AIDS Malignancy Conference. Journal of the National Cancer Institute Monographs. No. 23. Bethesda, Md.: National Cancer Institute, 1998:27-30.

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